KGA-2727
Product Specifications
CAS Number
666842-36-0
Target
SGLT
Related Pathways
GPCR/G Protein
Purity
0.9895
Bioactivity
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat) . KGA-2727 for the treatment of diabete.
Smiles
CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(OCCCNCCC(N)=O)cc1C
Molecular Formula
C26H40N4O8
Molecular Weight
536.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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