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KGA-2727

Product Specifications

CAS Number

666842-36-0

Target

SGLT

Related Pathways

GPCR/G Protein

Purity

0.9895

Bioactivity

KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat) . KGA-2727 for the treatment of diabete.

Smiles

CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(OCCCNCCC(N)=O)cc1C

Molecular Formula

C26H40N4O8

Molecular Weight

536.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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