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K-756

Product Specifications

CAS Number

130017-40-2

Target

PARP, Wnt/beta-catenin

Related Pathways

Chromatin/Epigenetic, Stem Cells, DNA Damage/DNA Repair, Cytoskeletal Signaling

Purity

0.9981

Bioactivity

K-756 is a direct and selective inhibitor of tankyrase (TNKS), inhibiting the ADP-ribosylation activity of TNKS1 [IC50 = 31 nM] and TNKS2 [IC50 = 36 nM].

Smiles

COc1cc2ncnc(N3CCC(CN4Cc5ccccc5NC4=O)CC3)c2cc1OC

Molecular Formula

C24H27N5O3

Molecular Weight

433.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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