K-756
Product Specifications
CAS Number
130017-40-2
Target
PARP|||Wnt/beta-catenin
Related Pathways
Chromatin/Epigenetic|||Stem Cells|||DNA Damage/DNA Repair|||Cytoskeletal Signaling
Purity
0.9981
Bioactivity
K-756 is a direct and selective inhibitor of tankyrase (TNKS), inhibiting the ADP-ribosylation activity of TNKS1 [IC50 = 31 nM] and TNKS2 [IC50 = 36 nM].
Smiles
COc1cc2ncnc(N3CCC(CN4Cc5ccccc5NC4=O)CC3)c2cc1OC
Molecular Formula
C24H27N5O3
Molecular Weight
433.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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