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K-252c

Product Specifications

CAS Number

85753-43-1

Target

PKC, Apoptosis, Antibacterial

Related Pathways

Apoptosis, Microbiology/Virology, Cytoskeletal Signaling, Chromatin/Epigenetic

Bioactivity

K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM) . K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.

Smiles

O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21

Molecular Formula

C20H13N3O

Molecular Weight

311.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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