K-252c
Product Specifications
CAS Number
85753-43-1
Target
PKC, Apoptosis, Antibacterial
Related Pathways
Apoptosis, Microbiology/Virology, Cytoskeletal Signaling, Chromatin/Epigenetic
Bioactivity
K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM) . K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.
Smiles
O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21
Molecular Formula
C20H13N3O
Molecular Weight
311.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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