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JTK-853

Product Specifications

CAS Number

954389-09-4

Target

Others|||HCV Protease

Related Pathways

Others|||Microbiology/Virology|||Proteases/Proteasome

Bioactivity

JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase, exhibiting effective antiviral activity in HCV replicon cells with EC50s of 0.38 ?M for genotype 1a H77 strain and 0.035 ?M for genotype 1b Con1 strain.

Smiles

C(NCC1=CC(F)=C(OC(F)(F)F)C=C1)(=O)[C@@H]2N(S(=O)(=O)C3=CC=C(C(F)(F)F)C=C3)CCN(C2)C4=NC=5C(S4)=CN=C(N5)C6CC6

Molecular Formula

C28H23F7N6O4S2

Molecular Weight

704.64

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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