JTK-853
Product Specifications
CAS Number
954389-09-4
Target
Others|||HCV Protease
Related Pathways
Others|||Microbiology/Virology|||Proteases/Proteasome
Bioactivity
JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase, exhibiting effective antiviral activity in HCV replicon cells with EC50s of 0.38 ?M for genotype 1a H77 strain and 0.035 ?M for genotype 1b Con1 strain.
Smiles
C(NCC1=CC(F)=C(OC(F)(F)F)C=C1)(=O)[C@@H]2N(S(=O)(=O)C3=CC=C(C(F)(F)F)C=C3)CCN(C2)C4=NC=5C(S4)=CN=C(N5)C6CC6
Molecular Formula
C28H23F7N6O4S2
Molecular Weight
704.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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