JNJ-5207787
Product Specifications
CAS Number
683746-68-1
Target
Neuropeptide Y Receptor, Others
Related Pathways
Others, Neuroscience, GPCR/G Protein
Bioactivity
JNJ-5207787 is a penetrates the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. It is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ-5207787 suppresses the binding of peptide YY with pIC50s of 7.0 and 7.1 for the human Y2 receptor and rat Y2 receptor, respectively.
Smiles
N(C(/C=C/C1=CC(C#N)=CC=C1)=O)(C=2C=C3C(=CC2)CCN3C(C)=O)C4CCN(CCC5CCCC5)CC4
Molecular Formula
C32H38N4O2
Molecular Weight
510.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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