JNJ-46281222
Product Specifications
CAS Number
1254980-38-5
Target
GluR
Related Pathways
Neuroscience
Bioactivity
JNJ-46281222 is a metabotropic glutamate (mGlu) 2-selective, highly potent positive allosteric modulator (PAM) with nanomolar affinity (Kd = 1.7 nM) and high modulatory potency (pEC50 = 7.71) .
Smiles
FC(F)(F)c1c(CN2CCC(CC2)c2ccccc2)ccn2c(CC3CC3)nnc12
Molecular Formula
C23H25F3N4
Molecular Weight
414.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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