JHU-083
Product Specifications
CAS Number
1998725-11-3
Target
Glutaminase|||RAAS
Related Pathways
Proteases/Proteasome|||Endocrinology/Hormones
Purity
0.9953
Bioactivity
JHU-083 is an orally available, blood-brain barrier-crossing, selective glutaminase antagonist that improves cognitive performance and normalizes abnormal hippocampal glutaminase activity in APOE4 mice.
Smiles
[C@H](NC([C@H](CC(C)C)N)=O)(CCC(C=[N+]=[N-])=O)C(OCC)=O
Molecular Formula
C14H24N4O4
Molecular Weight
312.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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