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JH-VIII-157-02

Product Specifications

CAS Number

1639422-97-1

Target

ALK, Microtubule Associated

Related Pathways

Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9958

Bioactivity

JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.

Smiles

CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1-c1cnn(CC(=O)N(C)C)c1

Molecular Formula

C28H27N5O2

Molecular Weight

465.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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