What is the catalog number for JH-RE-06?

The catalog number for JH-RE-06 is T15611.

What sizes are available for JH-RE-06?

JH-RE-06 is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does JH-RE-06 come in?

JH-RE-06 is available in 7 different pack sizes.

Is JH-RE-06 in stock?

JH-RE-06 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures JH-RE-06?

JH-RE-06 is manufactured by Molfinity.

What is the estimated delivery time for JH-RE-06?

Estimated delivery time for JH-RE-06 is approximately 10 business day(s), depending on your location.

JH-RE-06

Product Specifications

CAS Number

1361227-90-8

Target

DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

0.9929

Bioactivity

JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.