MKC8866
Product Specifications
CAS Number
1338934-59-0
Target
IRE1
Related Pathways
Cell Cycle/Checkpoint
Purity
0.99854
Bioactivity
MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 μM in human vitro) . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.
Smiles
COc1cc2c(C)c(CC(=O)N3CCOCC3)c(=O)oc2c(C=O)c1O
Molecular Formula
C18H19NO7
Molecular Weight
361.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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