MKC8866

Product Specifications

CAS Number

1338934-59-0

Target

IRE1

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9985

Bioactivity

MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 ?M in human vitro) . MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.

Smiles

COc1cc2c(C)c(CC(=O)N3CCOCC3)c(=O)oc2c(C=O)c1O

Molecular Formula

C18H19NO7

Molecular Weight

361.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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