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Incyclinide

Product Specifications

CAS Number

15866-90-7

Target

MMP

Related Pathways

Proteases/Proteasome

Purity

0.9799

Bioactivity

Chemically modified tetracyclines (CMTs) can inhibit MMPs, but lack antimicrobial activity. Nonantimicrobial derivative of tetracycline called incyclinide (COL-3, CMT-3) . Incyclinide (CMT-3) has been shown to experimentally suppress prostate cancer, colon adenocarcinoma and melanoma invasiveness in cell culture and to inhibit tumor growth and metastasis.

Smiles

[H][C@@]12Cc3cccc(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C[C@]1([H])C2

Molecular Formula

C19H17NO7

Molecular Weight

371.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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