Icatibant
Product Specifications
CAS Number
130308-48-4
Target
Bradykinin Receptor, Others
Related Pathways
Others, GPCR/G Protein
Bioactivity
Icatibant is a selective and specific antagonist of the bradykinin B2 receptor (IC50 and Ki: 1.07 nM and 0.798 nM respectively) .
Smiles
N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](Cc1cccs1)C(=O)N[C@@H](CO)C(=O)NC(=N)NCCC[C@H](N(C(=O)C1C[C@@H]2CCCC[C@@H]2N1)C(=O)[C@H]1Cc2ccccc2CN1)C(O)=O
Molecular Formula
C59H89N19O13S
Molecular Weight
1304.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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