Methyl gallate

Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.

Product Specifications

CAS Number

[99-24-1]

Product Name Alternative

Gallincin; NSC 363001

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; HIV; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Methyl_gallate.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC)C1=CC(O)=C(O)C(O)=C1

Molecular Formula

C8H8O5

Molecular Weight

184.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Kang MS, et al. Inhibitory effect of methyl gallate and gallic acid on oral bacteria. J Microbiol. 2008 Dec;46 (6) :744-50.|[2]Hsieh TJ, et al. Protective effect of methyl gallate from Toona sinensis (Meliaceae) against hydrogen peroxide-induced oxidative stress and DNA damage in MDCK cells. Food Chem Toxicol. 2004 May;42 (5) :843-50.|[3]Lee H, et al. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. J Immunol. 2010 Dec 1;185 (11) :6698-705.|[4]Wang CR, et al. First report on isolation of methyl gallate with antioxidant, anti-HIV-1 and HIV-1 enzyme inhibitory activities from a mushroom (Pholiota adiposa) . Environ Toxicol Pharmacol. 2014 Mar;37 (2) :626-37.