HQL-79
Product Specifications
CAS Number
162641-16-9
Target
Others, PGE Synthase
Related Pathways
Others, Immunology/Inflammation
Bioactivity
HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 μM and IC50: 6 μM) . It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.
Smiles
C(CN1CCC(CC1)OC(c1ccccc1)c1ccccc1)Cc1nnn[nH]1
Molecular Formula
C22H27N5O
Molecular Weight
377.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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