Halofantrine hydrochloride
Product Specifications
CAS Number
36167-63-2
Target
Others, Parasite, Potassium Channel, Antibiotic
Related Pathways
Membrane transporter/Ion channel, Others, Microbiology/Virology
Bioactivity
Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.
Smiles
Cl.FC(F)(F)C1=CC=C2C(=C1)C=3C=C(Cl)C=C(Cl)C3C=C2C(O)CCN(CCCC)CCCC
Molecular Formula
C26H31Cl3F3NO
Molecular Weight
536.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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