GSK2798745
Product Specifications
CAS Number
1419609-94-1
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4) . It is used in research for the treatment of pulmonary edema associated with congestive heart failure.
Smiles
CC(C)(O)c1cnc(cn1)N1C[C@@]2(CCC[C@](C)(Cn3cnc4ccc(cc34)C#N)C2)OC1=O
Molecular Formula
C25H28N6O3
Molecular Weight
460.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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