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GSK2194069

Product Specifications

CAS Number

1332331-08-4

Target

Fatty Acid Synthase, NADPH

Related Pathways

Metabolism

Purity

0.9984

Bioactivity

GSK2194069 is an active β-keto reductase (KR) -specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH.

Smiles

O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(cc2)-c2ccc3occc3c2)C1

Molecular Formula

C25H24N4O3

Molecular Weight

428.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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