GSK2194069
Product Specifications
CAS Number
1332331-08-4
Target
Fatty Acid Synthase, NADPH
Related Pathways
Metabolism
Purity
0.9984
Bioactivity
GSK2194069 is an active β-keto reductase (KR) -specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH.
Smiles
O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(cc2)-c2ccc3occc3c2)C1
Molecular Formula
C25H24N4O3
Molecular Weight
428.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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