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GNF351

Product Specifications

CAS Number

1227634-69-6

Target

Aryl Hydrocarbon Receptor

Related Pathways

Immunology/Inflammation

Purity

0.9904

Bioactivity

GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR) with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM) .

Smiles

CC(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(nc12)-c1cncc(C)c1

Molecular Formula

C24H25N7

Molecular Weight

411.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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