GNF351
Product Specifications
CAS Number
1227634-69-6
Target
Aryl Hydrocarbon Receptor
Related Pathways
Immunology/Inflammation
Purity
0.9904
Bioactivity
GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR) with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM) .
Smiles
CC(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(nc12)-c1cncc(C)c1
Molecular Formula
C24H25N7
Molecular Weight
411.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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