GNE-5729
Product Specifications
CAS Number
2026635-66-3
Target
IGluR, NMDAR
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Purity
0.9985
Bioactivity
GNE-5729 is a positive allosteric modulator of NMDAR with the advantage of crossing the blood-brain barrier and being orally available, with EC50 values of 37 nM, 4.7 μM and 9.5 μM for GluN2A, GluN2C and GluN2D, respectively, and can be used for the study of neurological and psychiatric disorders.
Smiles
ClC1=C(N2C(=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)C=C1)[C@H]4[C@H](C#N)C4
Molecular Formula
C17H10Cl2F3N5O
Molecular Weight
428.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-61474R-APC-Cy7 100 µL
ATG3 Recombinant Antibody, APC-Cy7 Conjugated
Sign In for Pricing
View Details 
K3206904 1.0 µg DNA
1700017D01Rik sgRNA CRISPR Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details 
LV623255 1.0 µg DNA
SETD7 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
Sign In for Pricing
View Details 
364544 200 µL
PCK2 (Phosphoenolpyruvate Carboxykinase 2, Mitochondrial, PEPCK, PEPCK2)
Sign In for Pricing
View Details