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GNE-0723

Product Specifications

CAS Number

1883518-31-7

Target

IGluR, NMDAR

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Purity

0.9991

Bioactivity

GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, with an EC50 of 21 nM for GluN2A. It can cross the blood-brain barrier (BBB) and improve outcomes in Dravet syndrome (DS) and Alzheimer's disease (AD) .

Smiles

C(F)(F)(F)C1=C(N2C(S1)=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)[C@H]4[C@H](C#N)C4

Molecular Formula

C16H8ClF6N5OS

Molecular Weight

467.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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