GNE-0723
Product Specifications
CAS Number
1883518-31-7
Target
IGluR|||NMDAR
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Purity
0.9991
Bioactivity
GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, with an EC50 of 21 nM for GluN2A. It can cross the blood-brain barrier (BBB) and improve outcomes in Dravet syndrome (DS) and Alzheimer's disease (AD) .
Smiles
C(F)(F)(F)C1=C(N2C(S1)=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)[C@H]4[C@H](C#N)C4
Molecular Formula
C16H8ClF6N5OS
Molecular Weight
467.78
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
130064-AP 100 µL
MYLIP (BZF1, IDOL, E3 Ubiquitin-protein Ligase MYLIP, Inducible Degrader of the LDL-receptor, Myosin Regulatory Light Chain Interacting Protein, MIR, BM-023, PP5242) (AP) discontinued
Ask
View Details 
