GNE-955
Product Specifications
CAS Number
1527523-39-2
Target
Pim
Related Pathways
Chromatin/Epigenetic, JAK/STAT signaling
Bioactivity
GNE-955 is a potent and orally active inhibitor of pan Pim kinase, with inhibition constants (Kis) of 0.018 nM, 0.11 nM, and 0.08 nM for Pim1, Pim2, and Pim3, respectively.
Smiles
O(C)C=1C(=NC(N2C=3C(C=N2)=CN=C(C3)C4=NC(C)=CN=C4)=CC1)N5C[C@@H](N)CCC5
Molecular Formula
C22H24N8O
Molecular Weight
416.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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