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GNE-781

Product Specifications

CAS Number

1936422-33-1

Target

Epigenetic Reader Domain, Histone Acetyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9992

Bioactivity

GNE-781 is a highly potent and selective inhibitor of CBP (IC50: 0.94 nM in TR-FRET assay) . GNE-781 also inhibits BRET and BRD4 (1) (IC50s: 6.2 nM and 5100 nM, respectively) .

Smiles

CNC(=O)N1CCc2c(C1)c(nn2C1CCOCC1)N1CCCc2cc(-c3cnn(C)c3)c(cc12)C(F)F

Molecular Formula

C27H33F2N7O2

Molecular Weight

525.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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