GNE-618
Product Specifications
CAS Number
1362151-42-5
Target
NAMPT
Related Pathways
Metabolism
Bioactivity
GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM) . GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.
Smiles
FC(F)(F)c1cccc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3[nH]ncc3c2)cc1
Molecular Formula
C21H15F3N4O3S
Molecular Weight
460.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2921219-01 20 µg
Recombinant Corynebacterium jeikeium Protein CrcB homolog 1 (crcB1)
Sign In for Pricing
View Details orb2921219-02 100 µg
Recombinant Corynebacterium jeikeium Protein CrcB homolog 1 (crcB1)
Sign In for Pricing
View Details 
MBS9912849 Inquire
Pigeon RNA-Binding Motif, Single-Stranded-Interacting Protein 3 (RBMS3) ELISA Kit
Sign In for Pricing
View Details 
MBS1148205 Inquire
Recombinant Bacillus cereus subsp. cytotoxis MutS2 protein (mutS2), partial
Sign In for Pricing
View Details 