GNE-618
Product Specifications
CAS Number
1362151-42-5
Target
NAMPT
Related Pathways
Metabolism
Bioactivity
GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM) . GNE-618 depletes NAD levels and induces tumor cell death. It has anti-tumor activity.
Smiles
FC(F)(F)c1cccc(c1)S(=O)(=O)c1ccc(CNC(=O)c2cnc3[nH]ncc3c2)cc1
Molecular Formula
C21H15F3N4O3S
Molecular Weight
460.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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