GNE-272
Product Specifications
CAS Number
1936428-93-1
Target
Epigenetic Reader Domain, Histone Acetyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
GNE-272 is a selective inhibitor of CBP/EP300 (IC50: 0.02, 0.03, and 13 μM for CBP, EP300, and BRD4, respectively) and a selective in vivo probe for CBP/EP300.
Smiles
CC(=O)N1CCc2c(C1)c(Nc1ccc(cc1F)-c1cnn(C)c1)nn2[C@H]1CCOC1
Molecular Formula
C22H25FN6O2
Molecular Weight
424.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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