Glesatinib
Product Specifications
CAS Number
936694-12-1
Target
TAM Receptor, c-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Glesatinib is an orally active and potent dual inhibitor of MET/SMO. Glesatinib is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.
Smiles
O(C1=C2C(C=C(S2)C3=CC=C(CNCCOC)C=N3)=NC=C1)C4=C(F)C=C(NC(NC(CC5=CC=C(F)C=C5)=O)=S)C=C4
Molecular Formula
C31H27F2N5O3S2
Molecular Weight
619.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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