GDC-0339
Product Specifications
CAS Number
1428569-85-0
Target
Pim
Related Pathways
Chromatin/Epigenetic, JAK/STAT signaling
Bioactivity
GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively) .
Smiles
Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1
Molecular Formula
C20H22F3N7OS
Molecular Weight
465.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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