Inavolisib
Product Specifications
CAS Number
2060571-02-8
Target
PI3K, Apoptosis
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling
Purity
0.999
Bioactivity
Inavolisib (GDC-0077) is an orally available selective PI3Kα inhibitor with an IC50 value of 0.038 nM.It exerts its activity by binding to the ATP-binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.
Smiles
C[C@H](Nc1ccc2-c3nc(cn3CCOc2c1)N1[C@@H](COC1=O)C(F)F)C(N)=O
Molecular Formula
C18H19F2N5O4
Molecular Weight
407.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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