Rapamycin
Product Specifications
CAS Number
53123-88-9
Target
Endogenous Metabolite|||Antifungal|||Autophagy|||mTOR|||FKBP|||Antibacterial|||Antibiotic
Related Pathways
Autophagy|||Immunology/Inflammation|||Microbiology/Virology|||Metabolism|||Apoptosis|||PI3K/Akt/mTOR signaling
Purity
0.998
Bioactivity
Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM) . Rapamycin has immunosuppressive activity and induces autophagy.
Smiles
[H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC
Molecular Formula
C51H79NO13
Molecular Weight
914.17
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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