Fluorofenidone
Product Specifications
CAS Number
848353-85-5
Target
Akt, PI3K, Others
Related Pathways
PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling
Purity
0.9987
Bioactivity
Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
Smiles
Cc1ccc(=O)n(c1)-c1cccc(F)c1
Molecular Formula
C12H10FNO
Molecular Weight
203.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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