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Fluorofenidone

Product Specifications

CAS Number

848353-85-5

Target

Akt, PI3K, Others

Related Pathways

PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling

Purity

0.9987

Bioactivity

Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.

Smiles

Cc1ccc(=O)n(c1)-c1cccc(F)c1

Molecular Formula

C12H10FNO

Molecular Weight

203.21

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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