FK706
Product Specifications
CAS Number
144055-55-0
Target
Serine Protease
Related Pathways
Proteases/Proteasome
Bioactivity
FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM) . FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase (IC50s: 22 nM and 100 nM, respectively) . FK706 has an anti-inflammatory effect.
Smiles
[Na].CC(C)[C@H](NC(=O)c1ccc(cc1)C(=O)NCC(O)=O)C(=O)N1CCC[C@H]1C(=O)NC(C(C)C)C(=O)C(F)(F)F
Molecular Formula
C26H33F3N4NaO7
Molecular Weight
593.556
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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