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Fenobam

Product Specifications

CAS Number

57653-26-6

Target

Apoptosis|||GluR

Related Pathways

Neuroscience|||Apoptosis

Purity

0.9993

Bioactivity

Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity (IC50: 84 nM) . Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively) .

Smiles

CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1

Molecular Formula

C11H11ClN4O2

Molecular Weight

266.68

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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