ESI-05
Product Specifications
CAS Number
5184-64-5
Target
CAMP, Acyltransferase
Related Pathways
Metabolism, GPCR/G Protein
Purity
0.98
Bioactivity
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM) . ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
Smiles
Cc1ccc(cc1)S(=O)(=O)c1c(C)cc(C)cc1C
Molecular Formula
C16H18O2S
Molecular Weight
274.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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