(±) -10-Hydroxycamptothecin
Product Specifications
CAS Number
64439-81-2
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Purity
0.9958
Bioactivity
(±) -10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Smiles
CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O
Molecular Formula
C20H16N2O5
Molecular Weight
364.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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