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(±) -10-Hydroxycamptothecin

Product Specifications

CAS Number

64439-81-2

Target

Topoisomerase

Related Pathways

DNA Damage/DNA Repair

Purity

0.9958

Bioactivity

(±) -10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

Smiles

CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)cc4cc3Cn1c2=O

Molecular Formula

C20H16N2O5

Molecular Weight

364.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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