Echinomycin
Product Specifications
CAS Number
512-64-1
Target
HIF/HIF Prolyl-Hydroxylase|||Antibiotic|||Antibacterial
Related Pathways
Chromatin/Epigenetic|||Metabolism|||Microbiology/Virology
Purity
0.95
Bioactivity
Echinomycin (Quinomycin A) is an antitumor antibiotic secondary metabolite isolated from Streptomyces, a quinoxaline antibiotic, a DNA doubly intercalating peptide, and inhibits hypoxia-inducible factor-1 (HIF-1) DNA binding activity. Echinomycin has potential anticancer activity and can be used to study triple-negative breast cancer.
Smiles
O=C(NC1C(=O)NC(C(=O)N(C)C2C(=O)N(C)C(C(=O)OCC(NC(=O)C3=NC4=CC=CC=C4N=C3)C(=O)NC(C(=O)N(C)C(C(=O)N(C)C(C(=O)OC1)C(C)C)C(SC)SC2)C)C(C)C)C)C5=NC6=CC=CC=C6N=C5
Molecular Formula
C51H64N12O12S2
Molecular Weight
1101.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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