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DNA2 inhibitor C5

Product Specifications

CAS Number

35973-25-2

Target

Others, DNA/RNA Synthesis

Related Pathways

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

Purity

0.9905

Bioactivity

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM) . DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.

Smiles

OC(=O)c1cnc2c(cccc2c1O)[N+]([O-])=O

Molecular Formula

C10H6N2O5

Molecular Weight

234.16

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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