DK419
Product Specifications
CAS Number
2102672-22-8
Target
Survivin, AMPK, c-Myc, Wnt/beta-catenin, CDK
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Stem Cells, Cytoskeletal Signaling, Chromatin/Epigenetic
Purity
0.9963
Bioactivity
DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM. DK419 decreases protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.
Smiles
FC(F)(F)c1nc2cc(Cl)cc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2[nH]1
Molecular Formula
C16H8ClF6N3O
Molecular Weight
407.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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