DK419

Product Specifications

CAS Number

2102672-22-8

Target

Survivin|||AMPK|||c-Myc|||Wnt/beta-catenin|||CDK

Related Pathways

Apoptosis|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Stem Cells|||Cytoskeletal Signaling|||Chromatin/Epigenetic

Purity

0.9963

Bioactivity

DK419 is an orally active inhibitor of Wnt/?-catenin signaling, with an IC50 of 0.19 ?M. DK419 decreases protein lelvels of Axin2, ?-catenin, c-Myc, Cyclin D1 and Survivin.It also induces production of pAMPK.

Smiles

FC(F)(F)c1nc2cc(Cl)cc(C(=O)Nc3ccc(cc3)C(F)(F)F)c2[nH]1

Molecular Formula

C16H8ClF6N3O

Molecular Weight

407.7

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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