Defactinib hydrochloride
Product Specifications
CAS Number
1073160-26-5
Target
FAK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling
Purity
0.9878
Bioactivity
Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK. Which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
Smiles
Cl.CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1
Molecular Formula
C20H22ClF3N8O3S
Molecular Weight
546.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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