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DBCO-PEG4-Maleimide

Product Specifications

CAS Number

1480516-75-3

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Purity

0.9951

Bioactivity

DBCO-PEG4-Maleimide is a non-cleavable PEG-based linker used in the synthesis of antibody–drug conjugates (ADCs) . DBCO-PEG4-Maleimide contains a dibenzocyclooctyne group, which enables strain-promoted alkyne–azide cycloaddition (SPAAC) with azide-functionalized biomolecules, supporting efficient construction of bioconjugates under copper-free click conditions.

Smiles

O=C1C=CC(=O)N1CCC(=O)NCCOCCOCCOCCOCCC(=O)NCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

Molecular Formula

C36H42N4O9

Molecular Weight

674.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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